Sort items by: Date | Alphabetical
|On Demand Webinar|| Highly Reactive Chemistry: Minimize Hazard and Risk |
Case studies are presented illustrating how to ensure safe development, scale-up and operation of highly reactive chemistry.
|On Demand Webinar|| Reducing the Risk of Highly Reactive Chemistry in Chemical R&D Part 2 |
Case studies are presented illustrating how to aid in the safe development, scale-up and operation of highly reactive chemistry.
|On Demand Webinar|| 20 Years of Reaction Calorimetry at Johnson and Johnson |
Learn how Johnson and Johnson avoids chemical reaction hazards using reaction calorimetry.
|On Demand Webinar|| Safe Scale-up of Chemical Processes at Chilworth |
This presentation discusses how to ensure the safety of a process, when they should be performed, and how the outcomes of the tasks should be integrated to maximize the benefit. The safety of a process is not purely the domain of chemical engineers. Chemists dictate the intrinsic hazards of the process.
|On Demand Webinar|| Avoiding Batch Failures via Scale Down Simulation of Exothermic Reactions in the Lab |
Breakthroughs in process operations and modeling are necessary to achieve energy and material efficiency gains supporting shorter development and scale-up times while improving safety and the environmental and economical profile of chemical processes at the same time. In parts, these breakthroughs are made possible thanks to the use of Process Analytical Techniques (PAT) and reactor systems designed for real-time in situ process monitoring and accurate process control, both at lab and plant scale. In this webinar, case studies will be presented exploring the use of real time calorimetry as a process analytical tool mimicking operating conditions of industrial reactors at lab scale – to prevent batch failures at plant scale.
|On Demand Webinar|| Safe Process Scale-up - A Case Study of Nitroalkane Chemistry by WeylChem |
WeylChem avoids process safety and thermal hazard analysis risks by studying heat generation. A scalable and cost efficient synthetic route to diformylarylbenzene was investigated. It involved a double formylation step that relies on the use of 2-nitropropane as a primary reagent. Due to the inherent energetic nature of nitroalkanes, a process safety assessment was necessary.
|On Demand Webinar|| Safe and Scalable Oxidation of Benzaldoximes |
A thermal analysis of a Oxidation of Benzaldoximes reaction is used to determine the heat flow in the presence of common additives to determine the most effective means of safe scale-up. Of the additives screened, aqueous HCl consistently avoided an induction period and enabled a dose-controlled process to be developed.
|On Demand Webinar|| Avoiding Incidents at Scale-up: Is Your Process Resistant Towards Maloperation? |
This webinar discusses how to perform safe scale-up of chemical processes and includes a close examination of thermal risks and hazards.
|On Demand Webinar|| Importance of Mixing for Heterogeneous, Continuous Processes |
Development of continuous processes is a chemical engineering challenge that requires a balance of heat transfer, mass transfer and kinetics. This webinar discusses how to simulate plant conditions and develop continuous processes.
|On Demand Webinar|| How To Win The Battle In The Chemical Process R&D Lab |
Chemical development is impacted by various economic drivers and requires changes to ensure success in the future. Companies have reacted to these drivers by implementing a lab of the future/tomorrow strategy.
|On Demand Webinar|| Chemical Process Development Methods Webinar |
Pharmaceutical and fine chemical companies are under pressure to bring products to market faster, at lower costs and with higher quality. The solutions implemented are based around deliverables in four main areas – deliver a process faster than using traditional methods, at lower cost, and with increased quality and robustness. This can be achieved by learning as much as possible about the nature of the chemical process under development as early as possible.
|On Demand Webinar|| Characterize, Optimize and Scale-up Pressure Reactions |
There is an increasing demand to run reactions at elevated pressure. Due to the nature of pressure chemistry, the reaction mass typically consists of multiple phases, e.g. liquid/gas or even liquid/solid/gas. As a result, the reaction is not only controlled by the usual parameters, such as temperature of the reaction mass or the concentration of the reactants, but also by parameters like gas feed, catalyst type, catalyst concentration, mixing and subsequently mass transfer. In fact, pressure chemistry is more challenging and requires robust equipment as well as control and data acquisition software.